Aerosol Generation

Aerosol Generation refers to the process of creating fine liquid or solid particles suspended in gas for inhalation delivery, enabling therapeutic agents to reach pulmonary or systemic targets via the respiratory tract. Particle size, distribution, and velocity critically determine deposition patterns across different respiratory regions.

The pharmaceutical industry develops aerosol generation technologies for respiratory medicines, pulmonary drug delivery, and inhaled vaccine platforms. Nebulisers, pressurised metered-dose inhalers, and dry powder inhalers employ different mechanisms producing distinct particle characteristics. Aerodynamic particle size distribution characterisation through cascade impaction guides formulation and device design. Inhalation toxicology assesses aerosol safety in preclinical studies. As interest grows in inhaled delivery of biologics and nucleic acid therapeutics, aerosol generation science continues advancing through innovative device technologies and formulation approaches enabling new routes of administration.